Edgar Prisco was a member of Los Priscos, and the younger brother of Ricardo Prisco and two older brothers. He was killed by the Search Bloc in a raid.
Edgar and his brothers ran a drug operation in Medellin, Colombia as associates of the Medellín cartel collective run by Pablo Escobar. In 1992, the Prisco accidentally led Search Bloc forces to a billiards house in Medellin after he used his brother's satellite phone to make calls to Escobar, with Edward Jacoby and Centra Spike monitoring them. Search Bloc troops threw flashbangs into the building and gunned Edgar down when he tried to shoot at them.